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KMID : 1190620140100010014
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Journal of the Korean Wound Care Society
2014 Volume.10 No. 1 p.14 ~ p.19
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Skin Graft Fixation Using Fast-clotting Fibrin Glue
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Han Hyun-Ho
Kang In-Sook
Moon Suk-Ho
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Abstract
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Sutures and staplers have been widely used for graft fixation, and since the 2000s, fibrin has also been used. To use fibrin, autologous blood is collected and processed, or commercial products are diluted to prepare low-concentration fibrin glues, requiring substantial time and effort. For graft fixation, a fast-clotting fibrin sealant containing 400 IU/ml thrombin was used for all subjects. At 5 days postoperatively, and the graft hematoma/seroma incidence and graft dislocation rates were investigated. At 30 days postoperatively, the graft necrosis and graft-take rates were investigated. The surface area was calculated using ImageJ (US National Institutes of Health, Bethesda, MD, USA). The size of the defect area ranged from 3 cm×2 cm to 22 cm×5 cm. At 5 days postoperatively, the mean hematoma/seroma incidence and graft dislocation rates were 7.84% and 1.29%, respectively. At 30 days postoperatively, the graft necrosis and graft-take rates were 0.76% and 99.24%, respectively. When high-concentration fast-clotting fibrin sealants were applied to skin grafts without a dilution process, no difficulty was experienced during the surgery, and the results were similar to those of slow-clotting fibrin sealants with excellent skin graft-take rates.
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KEYWORD
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Fibrin sealant, Thrombin, Split thickness skin graft
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